This article examines how various aspects of US politics and culture may define the boundaries of transnational online discourse. The argument presented focuses on two general categories by which these dynamics may emerge, namely systemic and agential factors. Systemic limitations include language, codes and protocols, algorithms, and parameters set by media specific terms of services. Agential factors are tied to specific sets of political and economic interests, legal frameworks or cultural norms, as well as individual forms of human agency involved in content moderation.